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High Purity Water Soluble Beta nicotinamide adenine dinucleotide

Active Pharmaceutical Ingredients

High Purity Water Soluble Beta nicotinamide adenine dinucleotide

Product Name: Beta-nicotinamide adenine dinucleotide NAD

Specifications: 99.60%

Appearance: White to off-white powder

CAS NO.:53-84-9

Test Method: HPLC

Process: NAD + is synthesized by two metabolic pathways: by a combination of existing components such as nicotinamide for recycling back to NAD +, or by de novo synthesis by amino acids. Most organisms synthesize NAD + from simple components can vary between organisms, but the common feature is the production of quinolinic acid (QA) between the amino acid-tryptophan in animals and some bacteria or aspartate in some bacteria and plants. Quinolinic acid was converted to nicotinic acid mononucleotide (NaMN) by transferring the biose phosphate moiety. The adenylate fraction is then transferred to form the nicotinic acid adenine dinucleotide (NAD). Finally, the nicotinate part of the NAD amides into the nicotinamide (Nam) part to form the NAD +. Further, some NAD + will be converted by the NAD + kinases into NADP +, phosphorylated NAD +. In most organisms, the enzyme makes ATP as a pathway into a phosphate group. Although several bacteria such as Mycobacterium tuberculosis and hyperthermophilic archaea use inorganic polyphosphate as alternative phosphate donors.

Sample: Free Sample

Stock: In Stock

Shelf Life: 2Years

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    Product Introduction

    Nicotinamide adenine dinucleotide,NAD, or coenzyme I, is a transacting proton (more accurately hydrogen ion) coenzyme, which appears in many metabolic reactions of cells. The NAD is composed of two nucleotides, so it is called a dinucleotide, one with adenine and the other with nicotinamide, and the two nucleotides are linked together by pyrophosphate. NAD exists in two forms: the oxidized form of NAD + and the reduced form of NADH. NADH carries a maximum of two protons (written as NADH + H +) with a standard electrode potential of-0.32V.
    Within the organism, NAD can be synthesized from simple building blocks with the amino acid tryptophan or aspartate. In an alternative way, taking more complex combinations of enzymes from food, this vitamin is called niacin. Similar compounds are released by reactions that resolve the NAD structure. These prefabricated components then pass through a recycling channel to recycle them into an active form. Some NAD is also converted to nicotinamide adenine dinucleotide phosphate (NADP); this associated coenzyme has a chemical composition similar to NAD but has different roles in metabolism. In metabolism, NAD + participates in redox reactions, carrying electrons from one reaction to another. Therefore, coenzymes exist in two forms in the cell: NAD + is an oxidant that accepts electrons from other molecules. The reaction forms NADH, which can then be used as a reducing agent. These electron-transfer reactions are a major function of the NAD. However, it is also used in other cellular processes, most notably for the substrates of the enzyme that add or remove the chemical groups in the protein. Due to the importance of these functions, the enzymes found in NAD metabolism are the targets of drugs. Although the positive charge of NAD + on a specific nitrogen atom is written to a plus, in most cases of physiological pH, it is actually a single-charged anion (negative charge 1), while NADH is a double-charged anion.

    β-烟酰胺腺嘌呤二核苷酸详情图12el

    Product Feature

    1.Improve metabolism
    NAD + is the energy supply molecule found in every cell of the body to metabolize, build new cells, resist free radicals and DNA damage, and send signals inside the cells, enabling mitochondria to convert the food we eat into the energy that our body needs to maintain all its functions. Also need to "turn off" the genes that accelerate the aging process.2.Free radical scavenger
    Thus, it plays a protective role in the growth of plants under osmotic stress, and for the accumulation of another important osmotic material in the vacuole, proline can play a role in regulating the cytoplasm osmotic balance.
    2.Improve the life cycle
    Studies in experimental animals and populations have shown substantial decreases in NAD + levels with age. This decline puts us at greater risk of nerve and muscle degeneration, decreased cardiometabolic health, and repair and resilience. Scientists at prestigious research institutes have been studying NAD + augmentation strategies as a treatment for degenerative conditions associated with aging.4. good flavor
    Flavor agent, coheat with sugar amino monohydrogen group reaction, can produce substances with special aroma

    3.strengthen your immune system
    β -Nicotinamide adenine dinucleotide, also known as oxidized Coenzyme I, is an important coenzyme, involved in the metabolism of cellular substances, energy synthesis, cellular DNA repair and other physiological activities, and plays an important role in the body's immune capacity.
     
    β-烟酰胺腺嘌呤二核苷酸详情图2g85

    Product Data Sheets

    Analysis Description Results
    Appearance White to off-white powder Confirm
    Water content <5% 0.033
    (ppm by GC)Ethanol <500 98
    Coliform <3 MPN/g N.D.
    Yeast and mold <10 CFU/g <10 CFU/g
     Salmonella   Not Detected N.D.
    Heavy metals (as Pb) <0.1 Conform
    Staphylococcus aureus  Not Detected N.D.
    Purity(% HPLC) >99.0% 0.996
    Total microbial count <300 CFU/g <10 CFU/g

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